who-approves-use-of-malaria-vaccine-with-adjuvant-tech

WHO Approves Use of Malaria Vaccine with Adjuvant Tech

 

Context: The R21/Matrix-M malaria vaccine developed by the University of Oxford and the Serum Institute of India, leveraging Novavax’s adjuvant technology, was recommended for use by the World Health Organization (WHO) after meeting required safety, quality and effectiveness standards.

 

Recommendations made by WHO

  • Following a detailed scientific review by the WHO’s independent advisory body, the Strategic Advisory Group of Experts (SAGE), and the Malaria Policy Advisory Group (MPAG), the R21/Matrix-M malaria vaccine has been recommended for use.
  • With the approval and recommendations by the WHO, additional regulatory approvals are expected to follow shortly and vaccine doses could be ready to begin wider roll-out as early as next year.

 

About the vaccine

  • The Matrix-M component is a proprietary saponin-based adjuvant from Novavax, which is licensed to the Serum Institute for use in endemic countries, while Novavax retains commercial rights in non-endemic countries.
  • The vaccine was developed by the Jenner Institute at Oxford University and the Serum Institute of India with support from the European and Developing Countries Clinical Trials Partnership (EDCTP), the Wellcome Trust, and the European Investment Bank (EIB).

 

Conclusion

The Serum Institute has already established production capacity for 100 million doses a year, which will be doubled over the next two years

This scale of production is critical because vaccinating those at high risk of malaria will be important in stemming the spread of disease, as well as protecting the vaccinated.

 

Imp for: UPSC Prelims, UPSC GS Mains Paper II, UPSC GS Mains Paper III

Topic: Health, Vaccination, Science & Technology, WHO

 

 

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